Compositions with a rheological modifier to reduce dissolution variability
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United States of America Patent
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Mar 6, 2018
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N/A
app pub date -
Dec 15, 2016
filing date -
Mar 15, 2013
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Abstract
The present disclosure provides compositions (e.g., extended release compositions) which exhibit a desirable pharmacokinetic profile of an active agent while providing reduced dissolution sample variability, e.g., in the form of reduced inter-capsule variability and/or a reduction in storage-time dependent change in mean release of the active agent from the composition. Related methods of making and administering the disclosed compositions and formulations are also provided.
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