Human keratinocytes PTCH1 cell line

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United States of America Patent

PATENT NO 9902934
SERIAL NO

14346872

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Abstract

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A cellular model is described for targeting dysregulation or inappropriate activation of the Sonic Hedgehog/Patched (SHH/PTCH) pathway. Also described, is a screening method using this cellular model to screen for pharmacological compounds that can treat or prevent skin cancer and, in particular, Basal Cell Carinoma (BCC) lesions.

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Patent Owner(s)

Patent OwnerAddress
GALDERMA RESEARCH & DEVELOPMENT06410 BIOT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Burty, Elodie Sourcieux-les-Mines, FR 5 1
Gache, Yannick Nice, FR 5 1
Magnaldo, Thierry Nice, FR 7 1

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