Pyrazolopyridine derivatives as modulators of TNF activity
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United States of America Patent
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Feb 27, 2018
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Dec 8, 2014
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Dec 9, 2013
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Abstract
A series of substituted pyrazolo[1,5-a]pyridine derivatives, being potent modulators of human TNFα activity, are accordingly of benefit in the treatment and/or prevention of various human ailments, including autoimmune and inflammatory disorders; neurological and neurodegenerative disorders; pain and nociceptive disorders; cardiovascular disorders; metabolic disorders; ocular disorders; and oncological disorders.
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