Nitrogenous heterocyclic derivatives and their application in drugs

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United States of America Patent

PATENT NO 9902712
APP PUB NO 20160355501A1
SERIAL NO

15034546

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Abstract

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The present invention relates to the field of medicine, provided herein are novel nitrogenous heterocyclic compounds, their preparation methods and their uses as drugs, especially for treatment and prevention of tissue fibrosis. Also provided herein are pharmaceutically acceptable compositions comprising the nitrogenous heterocyclic compounds and the uses of the compositions in the treatment of human or animal tissue fibrosis, especially for human or animal renal interstitial fibrosis, glomerular sclerosis, liver fibrosis, pulmonary fibrosis, IPF, peritoneal fibrosis, myocardial fibrosis, dermatofibrosis, postsurgical adhesion, benign prostatic hyperplasia, skeletal muscle fibrosis, scleroderma, multiple sclerosis, pancreatic fibrosis, cirrhosis, myosarcoma, neurofibroma, pulmonary interstitial fibrosis, diabetic nephropathy, alzheimer disease or vascular fibrosis.

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Patent Owner(s)

Patent OwnerAddress
SUNSHINE LAKE PHARMA CO LTDNORTHERN INDUSTRIAL AREA SONGSHAN LAKE DONGGUAN GUANGDONG 523000 523000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Liang Dongguan, CN 931 8928
Lin, Jihua Dongguan, CN 2 1
Lin, Runfeng Dongguan, CN 4 4
Wang, Xiaojun Dongguan, CN 139 517
Yu, Yi Dongguan, CN 261 4477
Zhang, Jiancun Dongguan, CN 28 327
Zhang, Yingjun Dongguan, CN 76 410

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