1,4-substituted piperidine derivatives
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United States of America Patent
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Feb 27, 2018
Grant Date -
Dec 22, 2016
app pub date -
Jun 17, 2016
filing date -
Jun 18, 2015
priority date (Note) -
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Abstract
Described herein are 1,4-substituted piperidine compounds according to Formula I that have demonstrated activity as fatty acid synthase inhibitors. Also described herein are pharmaceutical compositions containing the described 1,4-substituted piperidine compounds, and methods of treating diseases mediated by fatty acid synthase, by administering one or more of the compounds or pharmaceutical formulations described herein. Also described herein are methods of synthesizing the compounds described, including the described 1,4-substituted piperidine compounds and synthetic intermediates useful in those syntheses.
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