Methods for induction of antigen-specific immune tolerance

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United States of America Patent

PATENT NO 9901646
SERIAL NO

15232724

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Abstract

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Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.

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Patent Owner(s)

Patent OwnerAddress
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)EPFL - TTO EPFL INNOVATION PARK J LAUSANNE 1015

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dane, Karen Y Lausanne, CH 19 304
Hubbell, Jeffrey A Lausanne, CH 173 9467
Kontos, Stephan Lausanne, CH 20 193

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