Polymorphisms in ABCB1 associated with a lack of clinical response to medicaments

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United States of America Patent

PATENT NO 9901582
SERIAL NO

14800848

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Abstract

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The present invention relates to methods, compositions, kits and reagents for determining the prognosis of a clinical response in a human patient to a medicament which acts in the central nervous system (CNS) and which is a substrate of the ABCB1 protein. Further, the invention relates to a combination of medicaments for the treatment of human patients having specific polymorphisms in the ABCB1 gene.

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Patent Owner(s)

Patent OwnerAddress
MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E VMUNICH

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Holsboer, Florian München, DE 23 32
Müller-Myhsok, Bertram München, DE 7 14
Uhr, Manfred Stockdorf, DE 6 5

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