Asparaginic acid kinase III mutant and host cells and use thereof

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 9896734
APP PUB NO 20150337346A1
SERIAL NO

14437115

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

Provided in the present invention is an asparaginic acid kinase, and the 340th amino acid residue in the position of the amino acid sequence of the asparaginic acid kinase corresponding to the amino acid sequence shown in SEQ ID NO: 2 is a non-aspartic acid. The asparaginic acid of the present invention can efficiently relieve the feedback inhibition of L-lysine, and can be effectively used for the production of L-lysine. Also provided in the present invention are host cells comprising genes coding the asparaginic acid kinase and a method for producing L-lysine using the host cells or the asparaginic acid kinase. The asparaginic acid kinase of the present invention or the host cells comprising the asparaginic acid kinase of the present invention is also used to produce L-threonine, L-methionine, L-isoleucine or L-valine. Also provided in the present invention is a method of producing L-aspartyl-4-yl phosphoric acid using the asparaginic acid kinase or the host cells.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY CHINESE ACADEMY OF SCIENCES300308 NO 32 WEST SEVEN AIRPORT ECONOMIC ZONE DONGLI DISTRICT TIANJIN MUNICIPAL DISTRICT TIANJIN CITY 300308
COFCO BIOCHEMICAL (ANHUI) CO LTD233010 NO 1 COFCO AVENUE ANHUI BENGBU BENGBU CITY ANHUI PROVINCE 233010

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Qinggang Tianjin, CN 5 4
Liu, Jiao Tianjin, CN 52 79
Lu, Zongmei Anhui, CN 1 0
Luo, Hu Anhui, CN 6 209
Ma, Yanhe Tianjin, CN 30 5
Man, Yun Anhui, CN 1 0
Sun, Jibin Tianjin, CN 33 190
Xia, Linghe Anhui, CN 1 0
Yue, Guojun Anhui, CN 2 0
Zheng, Ping Tianjin, CN 74 636
Zhou, Yong Anhui, CN 177 1511
Zhou, Yongsheng Anhui, CN 7 7

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation

Maintenance Fees

Fee Large entity fee small entity fee micro entity fee due date
7.5 Year Payment $3600.00 $1800.00 $900.00 Aug 20, 2025
11.5 Year Payment $7400.00 $3700.00 $1850.00 Aug 20, 2029
Fee Large entity fee small entity fee micro entity fee
Surcharge - 7.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge - 11.5 year - Late payment within 6 months $160.00 $80.00 $40.00
Surcharge after expiration - Late payment is unavoidable $700.00 $350.00 $175.00
Surcharge after expiration - Late payment is unintentional $1,640.00 $820.00 $410.00