Use of EMT gene signatures in cancer drug discovery, diagnostics, and treatment
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United States of America Patent
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Feb 20, 2018
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Apr 25, 2012
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Apr 25, 2011
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Abstract
The present invention provides diagnostic methods for assessing the EMT status of tumor cells, and for predicting the effectiveness of treatment of a cancer patient with an EGFR or IGF-1R kinase inhibitor, utilizing an EMT gene signature index score. The present invention further provides methods for treating patients with cancer that incorporate these methods.
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