Leukaemia stem cell line, its method of production and uses thereof

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United States of America Patent

PATENT NO 9896663
SERIAL NO

15067991

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Abstract

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Bromodomain and extra terminal protein (BET) resistant leukemic cell lines and methods for producing such cell lines are described as are methods for using such cell lines in screening assays to identify therapeutic agents. The cell lines can be generated from haematopoietic stem and progenitor cells (HSPCs) that are clonally enriched by serially exposing c-kit positive cells to a BET inhibitor.

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Patent Owner(s)

Patent OwnerAddress
PETER MACCALLUM CANCER INSTITUTEEAST MELBOURNE VIC 3002

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dawson, Mark A Hawthorn East, AU 2 10
Fong, Chun Yew Melbourne, AU 1 6

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