Beta hairpin peptides having antiviral properties against Dengue virus

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United States of America Patent

PATENT NO 9896482
SERIAL NO

15119058

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Abstract

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The present invention discloses structurally constrained synthetic peptides that have been optimized for the formation of a beta hairpin structure. Said peptides are able to inhibit or attenuate Dengue virus (DENV) infections. The invention also discloses pharmaceutical compositions containing these synthetic peptides, which are useful for the prevention and/or treatment of DENV-caused infections. Likewise, the invention disclosed a method for treating infections caused by this virus.

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Patent Owner(s)

Patent OwnerAddress
CENTRO DE INGENIERIA GENETICA Y BIOTECNOLOGIALA HABANA 11600

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alvarez, Pérez Karen Havana, CU 1 0
Chinea, Santiago Glay Playa la Habana, CU 11 69
Falcón, Cama Viviana Playa la Habana, CU 2 2
Garateix, Suárez Rocío Havana, CU 1 0
Garay, Pérez Hilda Elisa Playa la Habana, CU 4 17
González, Blanco Sonia Playa la Habana, CU 3 3
González, López Luis Javier Playa la Habana, CU 11 18
Guirola, Cruz Osmany Havana, CU 8 64
Huerta, Galindo Vivian Playa la Habana, CU 6 59
Márquez, Perera Gabriel Jesús Playa la Habana, CU 1 0
Martín, Dunn Alejandro Miguel Playa la Habana, CU 3 12
Pupo, Gómez Dianne Havana, CU 1 0
Reyes, Acosta Osvaldo Playa la Habana, CU 23 51
Sarría, Núñez Mónica Havana, CU 2 12
Vázquez, Castillo Mariela Playa la Habana, CU 1 0
Yero, Díaz Alexis Havana, CU 1 0

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