Histone demethylase inhibitors
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United States of America Patent
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Feb 20, 2018
Grant Date -
Jul 7, 2016
app pub date -
Mar 15, 2016
filing date -
Sep 16, 2014
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Abstract
The present invention relates generally to compositions and methods for treating cancer and neoplastic diseases. Provided herein are substituted imidazole-pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition of histone demethylase enzymes. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as pancreatic cancer, prostate cancer, breast cancer, bladder cancer, lung cancer, gastric cancer, leukemia and/or melanoma and the like.
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