Simian adenoviral vectors encoding malaria antigen
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United States of America Patent
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Feb 20, 2018
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Apr 10, 2008
filing date -
Apr 10, 2007
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Abstract
The invention provides recombinant adenoviral vectors which are capable of eliciting immunity against the pre-erythrocytic stage of the life cycle of the malaria parasite. In particular, the invention provides a recombinant, replication deficient simian adenoviral vector which encodes an antigen comprising the thrombospondin-related adhesion protein (TRAP), and also immunogenic compositions (e.g. vaccines) comprising the vector and methods of using such compositions.
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