Pharmaceutical composition having preventative or treatment effect on inflammatory bowel diseases
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United States of America Patent
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Feb 20, 2018
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N/A
app pub date -
Jul 3, 2013
filing date -
Jul 3, 2012
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Abstract
The present invention relates to a pharmaceutical composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for suppressing the occurrence of inflammatory bowel diseases due to cigarette smoke, a method for preventing or treating inflammatory bowel diseases, a method for suppressing the expression of inflammatory cytokines by using the composition, and to a food composition, which contains a mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, for preventing or ameliorating inflammatory bowel diseases due to cigarette smoke. The pharmaceutical composition, according to the present invention, contains the mixture of extracts of Stemonae Radix, Asparagi Tuber, Scutellariae Radix, Schisandrae Fructus, Rehmanniae Radix Preparata, Armeniacae Semen, and Moutan Cortex Radicis, thereby reducing the level of MMP12 expression that is known to destroy IL-1β, TNF-α, IL-6 and MCP-1, which are inflammatory cytokines that accompany the inflammatory bowel diseases, elastin, and collagen, and thus can be widely used in developing a safe and effective inflammatory bowel disease treating agent.
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