Compositions comprising decitabine and tetrahydrouridine and uses thereof
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United States of America Patent
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Feb 20, 2018
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app pub date -
Feb 16, 2016
filing date -
Dec 22, 2008
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Abstract
Embodiments of compositions and methods for the treatment of blood disorders and malignancies in a subject are described herein. In one embodiment, a composition for the treatment of a blood disorder or a malignancy in a subject comprises decitabine, tetrahydrouridine, and an excipient. In another embodiment, a method for the treatment of a blood disorder or a malignancy in a subject comprises the oral administration of a composition comprising decitabine and tetrahydrouridine. In some examples, the composition may be administered 1-3 times weekly.
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