Aliphatic amine polymer salts for tableting
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United States of America Patent
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Feb 20, 2018
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app pub date -
Dec 14, 2016
filing date -
Nov 1, 2004
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Abstract
The tablets, compositions and methods of the present invention, comprising a carbonate salt of an aliphatic amine polymer and s monovalent anion can prevent or ameliorate acidosis, in particular acidosis in patients with renal disease. The tablets and compositions of the present invention maintain a disintegration time of no greater than 30 minutes at 37° C. and at pH of at least 1 for a period of at least ten weeks at 60° C. Furthermore, the tablets are stable for extended periods of time without the need for specialized storage conditions.
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