Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
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United States of America Patent
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Feb 13, 2018
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Mar 24, 2016
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Jul 12, 2007
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Abstract
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
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