Tools and methods for expression of membrane proteins
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United States of America Patent
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Feb 13, 2018
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app pub date -
Jan 21, 2013
filing date -
Jan 19, 2012
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Abstract
The disclosure relates cells or cellular systems that express both a membrane protein and a binding domain directed to the membrane protein. Also, methods are provided that use such cells or cellular systems to produce higher amounts of the membrane proteins. Further, the cells or cellular systems can be used as tools for the structural and functional characterization of membrane proteins, as well as for screening and drug discovery efforts targeting membrane proteins.
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