Oral vaccine having improved cellular immunity induction potency
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United States of America Patent
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Feb 13, 2018
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Apr 18, 2014
filing date -
Apr 19, 2013
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Abstract
An oral preparation for the prophylaxis or treatment of a disease with infection by a pathogen, containing a killed lactic acid bacterium expressing, on the surface, an antigen of the pathogen, or a microparticulated form thereof, which has an average particle size of 2.68-30 μm. An oral preparation for inducing cellular immunity to a target antigen, containing a killed lactic acid bacterium expressing the target antigen on the surface or a microparticulated form thereof, which has a particle size of 2.68-30 μm.
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