MALDI analysis of hydrophobic compounds using 2(3),5-dihydoxybenzoate with a long alkyl chain as an additive to MALDI matrix
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United States of America Patent
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Feb 6, 2018
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Sep 24, 2014
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Mar 27, 2014
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Abstract
The present invention provides a mass spectrometry method that can achieve analysis with high sensitivity using a matrix additive capable of improving ionization efficiency in mass spectrometry. A mass spectrometry method comprising the steps of: forming a mixed crystal for mass spectrometry on a target plate for mass spectrometry, the mixed crystal comprising a sample to be analyzed, a matrix, and a matrix additive selected from the group consisting of a 2,5-dihydroxybenzoate and a 3,5-dihydroxybenzoate that are represented by the following formula (I):
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