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• 15 United States
• 10 France
• 8 Japan
• 7 China
• 5 Korea
• 2 Other

Patent Owner(s)

Patent Owner	Address
HOWARD HUGHES MEDICAL INSTITUTE	4000 JONES BRIDGE ROAD CHEVY CHASE MD 20815-6789

International Classification(s)

• C07H:SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTI....
• A61K:PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOS....
• C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF

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Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Flotte, Terence	Holden, US	23	871
Mueller, Christian	Worcester, US	165	1577
Zamore, Phillip D	Northborough, US	101	5537

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Maintenance Fees

Fee	Large entity fee	small entity fee	micro entity fee	due date
7.5 Year Payment	$3600.00	$1800.00	$900.00	Aug 6, 2025
11.5 Year Payment	$7400.00	$3700.00	$1850.00	Aug 6, 2029

Fee	Large entity fee	small entity fee	micro entity fee
Surcharge - 7.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge - 11.5 year - Late payment within 6 months	$160.00	$80.00	$40.00
Surcharge after expiration - Late payment is unavoidable	$700.00	$350.00	$175.00
Surcharge after expiration - Late payment is unintentional	$1,640.00	$820.00	$410.00

DATE PUBLISHED	PUBLICATION/PATENT NO.	PUBLICATION TYPE
February 06, 2018	US,9885057,B2   US9885057B2	GRANTED PATENT AS SECOND PUBLICATION
June 08, 2017	US,20170159071,A9   US20170159071A9	CORRECTED PATENT APPLICATION
June 30, 2016	US,20160186211,A1   US20160186211A1	FIRST PUBLISHED PATENT APPLICATION

Full Text

US Patent No: 9885057

RAAV-based compositions and methods for treating alpha-1 anti-trypsin deficiencies

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