Methods for treating apolipoprotein E4-associated disorders

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United States of America Patent

PATENT NO 9885039
SERIAL NO

14668909

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Abstract

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The present disclosure provides a method of increasing the functionality of a GABAergic interneuron in the hilus of the hippocampus of an individual having at least one apolipoprotein E4 (apoE4) allele. The method generally involves reducing tau levels in the interneuron.

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Patent Owner(s)

  • THE J. DAVID GLADSTONE INSTITUTES

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andrews-Zwilling, Yaisa San Francisco, US 3 4
Huang, Yadong San Francisco, US 32 150

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