Fused pyrroledicarboxamides and their use as pharmaceuticals

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United States of America Patent

PATENT NO 9884860
SERIAL NO

15041541

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Abstract

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The present invention relates in fused pyrroledicarboxamides of the formula (I), in which R1 to R9, X, m and n are as defined in claims. The compounds of the formula (I) are inhibitors of the acid-sensitive potassium channel TASK-1 and suitable for the treatment of TASK-1 channel-mediated diseases such as arrhythmias, in particular atrial arrhythmias like atrial fibrillation or atrial flutter, and respiratory disorders, in particular sleep-related respiratory disorders like sleep apnea, for example.

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SANOFI54 RUE LA BOÉTIE PARIS 75008

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bialy, Laurent Frankfurt am Main, DE 9 30
Hessler, Gerhard Frankfurt am Main, DE 35 450
Lorenz, Katrin Frankfurt am Main, DE 31 260
Steinmeyer, Klaus Frankfurt am Main, DE 9 46
Wirth, Klaus Frankfurt am Main, DE 83 461

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