Salt and crystal forms of PLK-4 inhibitor
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United States of America Patent
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Feb 6, 2018
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app pub date -
Oct 17, 2014
filing date -
Oct 18, 2013
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Abstract
A fumarate salt and a maleate salt of compound (I) represented by the following structural formula, as well as their corresponding pharmaceutical compositions, are disclosed. Particular single crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are characterized by a variety of properties and physical measurements. Methods of preparing specific crystalline forms of 1:1 compound (I) fumarate and 1:1 compound (I) maleate are also disclosed. The present invention also provides methods of treating a subject with a cancer. Compound
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