PGAM1 inhibitors and methods related thereto

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United States of America Patent

PATENT NO 9884815
SERIAL NO

14349550

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Abstract

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In certain embodiments, the disclosure relates to methods of treating or preventing a PGAM1 mediated condition such as cancer or tumor growth comprising administering an effective amount of PGAM1 inhibitor, for example, an anthracene-9,10-dione derivative to a subject in need thereof. In certain embodiments, the disclosure relates to methods of treating or preventing cancer, such as lung cancer, head and neck cancer, and leukemia, comprising administering a therapeutically effective amount of a pharmaceutical composition comprising a compound disclosed herein or pharmaceutically acceptable salt to a subject in need thereof.

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Patent Owner(s)

Patent OwnerAddress
EMORY UNIVERSITYATLANTA GEORGIA 30322

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Jing Atlanta, US 545 3366
Hitosugi, Taro Decatur, US 15 102
Kang, Sumin Decatur, US 28 27

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