Bile acid-basic amino acid conjugates and uses thereof

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United States of America Patent

PATENT NO 9884066
SERIAL NO

14895723

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Abstract

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Compositions and methods for treating diseases or disorders associated with the metabolic syndrome using conjugates of bile acids with basic amino acids or a decarboxylated amino acid such as agmatine are provided. Further provided are bile acid-basic amino acid conjugates including chenodeoxycholic acid with an amino acid selected from arginine, lysine, histidine, ornithine or a decarboxylated amino acid such as agmatine.

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Patent Owner(s)

Patent OwnerAddress
YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTDHI TECH PARK EDMOND J SAFRA CAMPUS GIVAT RAM P O BOX 39135 JERUSALEM 91390

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Madar, Zecharia Rehovot, IL 4 21
Obercyger, Michal Ramat Gan, IL 1 4
Sasson, Shlomo Jerusalem, IL 3 5
Tirosh, Oren Ness Ziona, IL 29 1408
Voloshin, Ira Ashkelon, IL 1 4

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