Hepatitis B variants with reduced sensitivity to therapeutic compounds, their detection and uses thereof
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United States of America Patent
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Jan 30, 2018
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Mar 31, 2009
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Apr 5, 2008
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Abstract
The present invention is a diagnostic kit and materials for: 1) the prediction of the long-term response of a chronic hepatitis B virus (HBV) carrier to treatment with nucleoside/nucleotide analog, or their combination; 2) the detection of HBV variants that exhibit reduced reactivity to antibody detection; 3) the detection of HBV variants in the precore/core region that negatively affect the course of liver disease; 4) the identification of the HBV genotype.
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