Combination of biomarkers for the prognosis of response or non-response to an anti-HCV treatment

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United States of America Patent

PATENT NO 9879320
SERIAL NO

13983405

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The application concerns means for predicting whether a subject infected with one or more HCVs has a high probability of responding to an anti-HCV treatment which will comprise the administration of interferon and of ribavirin or whether, in contrast, that subject has a high probability of not responding to that anti-HCV treatment. The means of the invention in particular involve assaying the levels of expression of selected genes, said selected genes being:

    at least one gene from among MBL2, LGALS3BP and IL8, andat least one gene from among G1P2, CCL21 and CXCL10, andoptionally, at least one gene from among AFP, CRP, CXCL11, CXCL6, CXCL9, FGF7, MDK, MMP2, SFN, TGFB2 and VEGFD.

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Patent Owner(s)

Patent OwnerAddress
BIO-RAD EUROPE GMBHHOLBEINSTRASSE 75 BASEL 4051

International Classification(s)

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  • 2012 Application Filing Year
  • C12Q Class
  • 2418 Applications Filed
  • 1732 Patents Issued To-Date
  • 71.63 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201220132014201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Afshar, Mohammad Paris, FR 11 69
Asselah, Tarik Paris, FR 8 39
Batxelli, Isabelle Catherine Aigues-vives, FR 8 36
Bieche, Ivan Suresnes, FR 8 33
Jullian, Nathalie Montrouge, FR 5 25
Marcellin, Patrick Paris, FR 8 42
Mathieu, Eve Laure Montpellier, FR 5 25
Vidaud, Michel Fontenay Sous Bois, FR 9 36
Watelet, Bénédicte Saint Clement de Riviere, FR 6 29

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3285212917835231494333601 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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