Non-viral episomal suicide construct
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United States of America Patent
Stats
-
Jan 30, 2018
Issued Date -
N/A
app pub date -
Feb 27, 2013
filing date -
Mar 5, 2012
priority date (Note) -
In Force
status (Latency Note)
Importance
Abstract
The invention includes compositions and methods for the selective expression of a target gene in a subset of cells. In certain embodiments, the present invention includes a construct comprising a first nucleic acid sequence comprising an episomal maintenance element and a second nucleic acid sequence comprising a target gene wherein the expression of the episomal maintenance element is regulated by a constitutive promoter and the expression of the target gene is regulated by a non-constitutive promoter. The construct is able to maintain episomal state, no matter whether the target gene is expressed in the cell.
First Claim
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International Classification(s)
- 2013 Application Filing Year
- C12N Class
- 5078 Applications Filed
- 4006 Patents Issued To-Date
- 78.89 % Issued To-Date
Cited Art Landscape
Patent Citation Ranking
- 0 Citation Count
- C12N Class
- 0 % this patent is cited more than
- 7 Age
Maintenance Fees
| Fee | Large entity fee | small entity fee | micro entity fee | due date |
|---|---|---|---|---|
| 7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Jul 30, 2025 |
| 11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jul 30, 2029 |
