Constructs and methods for genome editing and genetic engineering of fungi and protists

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United States of America Patent

PATENT NO 9879270
SERIAL NO

14826566

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Provided herein are constructs for genome editing or genetic engineering in fungi or protists, methods of using the constructs and media for use in selecting cells. The construct include a polynucleotide encoding a thymidine kinase operably connected to a promoter, suitably a constitutive promoter; a polynucleotide encoding an endonuclease operably connected to an inducible promoter; and a recognition site for the endonuclease. The constructs may also include selectable markers for use in selecting recombinations.

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Patent Owner(s)

Patent OwnerAddress
WISCONSIN ALUMNI RESEARCH FOUNDATION614 WALNUT STREET MADISON WI 53726

International Classification(s)

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  • 2015 Application Filing Year
  • C12Q Class
  • 3483 Applications Filed
  • 2244 Patents Issued To-Date
  • 64.43 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances201520162017201820192020202120222023202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Alexander, William Gerald Madison, US 4 103
Hittinger, Christopher Todd Madison, US 4 103

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Patent Citation Ranking

  • 43 Citation Count
  • C12Q Class
  • 99.26 % this patent is cited more than
  • 7 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges3285212917835231494333601 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +020040060080010001200140016001800200022002400260028003000320034003600

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