Genetic variations associated with drug resistance

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United States of America Patent

PATENT NO 9879267
SERIAL NO

12922420

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Abstract

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Methods and compositions are provided to determine if a cancer is resistant to treatment with anti-mitotic agents, including treatment with T-DM1. The methods relate to determining if the ABCC3 gene is amplified and/or overexpressed in the cancer.

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Patent Owner(s)

Patent OwnerAddress
GENENTECH INC1 DNA WAY SOUTH SAN FRANCISCO CA 94080-4990

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Amler, Lukas C Foster City, US 15 359
Cavet, Guy Burlingame, US 6 175
Lackner, Mark South San Francisco, US 7 7
O'Brien, Carol Pacifica, US 3 1
Pandita, Ajay Redwood City, US 2 1

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