Method of viral production in cells
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United States of America Patent
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Jan 30, 2018
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N/A
app pub date -
Feb 15, 2012
filing date -
Mar 14, 2011
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Abstract
A method of using a cell to produce virus is provided involving growing cells under hyperosmotic conditions during a growth phase of the cells, infecting or transfecting the cells grown under hyperosmotic conditions with a virus, and maintaining the infected or transfected cells under less stressful conditions during a production phase of the infected or transfected cells to produce more of the virus. Viral productivity is improved by this method.
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