Macrocyclic inhibitors of the PD-1/PD-L1 and CD80(B7-1)/PD-L1 protein/protein interactions

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United States of America Patent

PATENT NO 9879046
APP PUB NO 20160340391A1
SERIAL NO

15204627

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Abstract

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The present disclosure provides novel macrocyclic peptides which inhibit the PD-1/PD-L1 and PD-L1/CD80 protein/protein interaction, and thus are useful for the amelioration of various diseases, including cancer and infectious diseases.

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Patent Owner(s)

Patent OwnerAddress
BRISTOL-MYERS SQUIBB COMPANYROUTE 206 AND PROVINCE LINE ROAD PRINCETON NEW JERSEY 08543 UNITED STATES OF AMERICA

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Allen, Martin Patrick Flemington, US 22 228
Bowsher, Michael S Prospect, US 26 172
Boy, Kenneth M Durham, US 34 330
Gillis, Eric P Cheshire, US 58 312
Langley, David R Meriden, US 54 1249
Miller, Michael Matthew Lambertville, US 10 172
Mull, Eric Guilford, US 30 328
Reid, Patrick C Tokyo, JP 8 120
Scola, Paul Michael Glastonbury, US 101 2080
Sun, Li-Qiang Glastonbury, US 57 943
Yeung, Kap-Sun Madison, US 67 826

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