GABAA agonists and methods of using to control airway hyperresponsiveness and inflammation in asthma

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United States of America Patent

PATENT NO 9879020
SERIAL NO

14429808

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Abstract

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Novel methods of treating inflammation and airway constriction using GABAergic compounds with reduced benzo-diazepine-like CNS activity are provided. Novel compounds which selectively target alpha-4 and alpha-5 GABAA receptors and methods of using those compounds to treat bronchoconstriction and inflammation are provided herein.

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Patent Owner(s)

Patent OwnerAddress
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKOFFICE OF THE GENERAL COUNSEL 412 LOW MEMORIAL LIBRARY MAIL CODE 4308 535 WEST 116TH STREET NEW YORK NY 10027

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Arnold, Alexander E Milwaukee, US 7 1
Cook, James M Whitefish Bay, US 49 405
Emala, Charles W Woodcliff Lake, US 3 0
Gallos, George Tenafly, US 2 0
Stafford, Douglas C Fitchburg, US 15 150
Stephen, Michael Rajesh Milwaukee, US 5 0

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