Polypeptide and lipophilic moiety conjugate compositions, formulations, and uses related thereto
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United States of America Patent
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Jan 30, 2018
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May 17, 2013
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May 18, 2012
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Abstract
In certain embodiments, this disclosure relates to pharmaceutical formulations for polypeptide and lipophilic moiety conjugates suitable for injection into humans and other animals and methods of preparation. In certain embodiments, the disclosure relates to a method of preparing the formulation comprising lyophilizing, solubilizing in ammonium acetate, filtering to create mono-disperse particles, re-lyophilizing, and solubilizing the micelles in a dextrose solution for injection.
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