Compositions comprising NDGA derivatives and sorafenib and their use in treatment of cancer
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United States of America Patent
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Jan 30, 2018
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app pub date -
Feb 4, 2013
filing date -
Feb 3, 2012
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Abstract
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.
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