RNA-mediated gene assembly from DNA oligonucleotides
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
-
Jan 23, 2018
Grant Date -
Aug 29, 2013
app pub date -
Feb 8, 2013
filing date -
Feb 10, 2012
priority date (Note) -
In Force
status (Latency Note)
![]() |
A preliminary load of PAIR data current through [] has been loaded. Any more recent PAIR data will be loaded within twenty-four hours. |
PAIR data current through []
A preliminary load of cached data will be loaded soon.
Any more recent PAIR data will be loaded within twenty-four hours.
![]() |
Next PAIR Update Scheduled on [ ] |

Importance

US Family Size
|
Non-US Coverage
|
Patent Longevity
|
Forward Citations
|
Abstract
The present invention is directed to methods and materials for RNA-mediated gene assembly from oligonucleotide sequences. In some embodiments, the oligonucleotides used for gene assembly are provided in an array format. An RNA polymerase promoter is appended to surface-bound oligonucleotides and a plurality of RNA copies of each oligonucleotide are then produced with an RNA polymerase. These RNA molecules self-assemble into a desired full-length RNA transcript by hybridization and ligation. The resulting RNA transcript may then be converted into double strand DNA useful in a variety of applications including protein expression.
First Claim
all claims..Other Claims data not available
Family
Country | kind | publication No. | Filing Date | Type | Sub-Type |
---|---|---|---|---|---|
WO | A1 | WO2013119948 | Feb 08, 2013 | Patent | Application |
Type : Patent Sub-Type : Application | |||||
INTERNATIONAL APPLICATION PUBLISHED WITH INTERNATIONAL SEARCH REPORT | RNA-MEDIATED GENE ASSEMBLY FROM DNA OLIGONUCLEOTIDES | Aug 15, 2013 | |||
US | B2 | US11753667 | Dec 12, 2017 | Patent | Grant |
Type : Patent Sub-Type : Grant | |||||
GRANTED PATENT AS SECOND PUBLICATION | RNA-mediated gene assembly from DNA oligonucleotides | Sep 12, 2023 |
- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
WISCONSIN ALUMNI RESEARCH FOUNDATION | 614 WALNUT STREET 13TH FLOOR MADISON WI 53726 |
International Classification(s)

- 2013 Application Filing Year
- C12P Class
- 1593 Applications Filed
- 1388 Patents Issued To-Date
- 87.14 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Smith, Lloyd | Madison, US | 14 | 206 |
# of filed Patents : 14 Total Citations : 206 | |||
Wu, Cheng-Hsien | Madison, US | 195 | 5583 |
# of filed Patents : 195 Total Citations : 5583 |
Cited Art Landscape
- No Cited Art to Display

Patent Citation Ranking
- 0 Citation Count
- C12P Class
- 0 % this patent is cited more than
- 7 Age
Forward Cite Landscape
- No Forward Cites to Display

Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
---|---|---|---|---|
7.5 Year Payment | $3600.00 | $1800.00 | $900.00 | Jul 23, 2025 |
11.5 Year Payment | $7400.00 | $3700.00 | $1850.00 | Jul 23, 2029 |
Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge - 7.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge - 11.5 year - Late payment within 6 months | $160.00 | $80.00 | $40.00 |
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
Full Text

Legal Events
Date | Code | Event | Description |
---|---|---|---|
May 21, 2021 | MAFP | MAINTENANCE FEE PAYMENT | free format text: PAYMENT OF MAINTENANCE FEE, 4TH YR, SMALL ENTITY (ORIGINAL EVENT CODE: M2551); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY year of fee payment: 4 |
Jan 23, 2018 | I | Issuance | |
Jan 03, 2018 | STCF | INFORMATION ON STATUS: PATENT GRANT | free format text: PATENTED CASE |
Aug 29, 2013 | P | Published | |
Feb 14, 2013 | AS | ASSIGNMENT | free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SMITH, LLOYD;WU, CHENG-HSIEN;REEL/FRAME:029923/0723 Owner name: WISCONSIN ALUMNI RESEARCH FOUNDATION, WISCONSIN Effective Date: Feb 14, 2013 |
Feb 14, 2013 | AS | ASSIGNMENT | free format text: CONFIRMATORY LICENSE;ASSIGNOR:WISCONSIN ALUMNI RESEARCH FOUNDATION;REEL/FRAME:029818/0379 Owner name: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF Effective Date: Feb 14, 2013 |
Feb 08, 2013 | F | Filing |

Matter Detail

Renewals Detail
