Production of fully processed and functional factor X in a furin-secreting mammalian expression system

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United States of America Patent

PATENT NO 9873892
SERIAL NO

14824927

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Abstract

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Disclosed herein are methods for production of fully-processed mature Factor X in an expression system producing a controlled amount of furin between 50 U/mL and 300 U/mL of culture supernatant. Also disclosed are transformed cells, expression systems, and expression vectors for the expression of furin and Factor X.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA PHARMACEUTICAL COMPANY LIMITED1-1 DOSHOMACHI 4-CHOME CHUO-KU OSAKA-SHI OSAKA 541-8645

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Böhm, Ernst Vienna, AT 5 2
Dockal, Michael Vienna, AT 47 164
Horling, Franziska Gänserndorf, AT 13 22
Koehn, Jadranka Vienna, AT 4 1

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