Stable and soluble antibodies inhibiting VEGF
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United States of America Patent
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Jan 23, 2018
Grant Date -
Oct 1, 2015
app pub date -
Jun 16, 2015
filing date -
Jun 25, 2008
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Abstract
The present invention relates to soluble and stable anti-VEGF imunobinders comprising CDRs from rabbit monoclonal antibodies. Said antibodies are designed for the diagnosis and/or treatment of VEGF-mediated disorders. The hybridomas, nucleic acids, vectors and host cells for expression of the recombinant antibodies of the invention, methods for isolating them and the use of said antibodies in medicine are also disclosed.
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