Photoimmunoconjugates for use in photodynamic therapy

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United States of America Patent

PATENT NO 9872904
SERIAL NO

14381386

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Abstract

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A compound comprising

    a photosensitizer covalently coupled toa protein selected from the group consisting ofantibodies or their derivatives or fragments thereof, synthetic peptides such as scFv, mimotopeswhich bind CD antigens, cytokine receptors, interleukin receptors, hormone receptors, growth factor receptors, more particularly tyrosine kinase growth factor receptor of the ErbB family, whereinthe photosensitizer is coupled to the binding protein via O6-alkylguanine-DNA alkyltransferase (hAGTm), a modified human DNA repair protein.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF CAPE TOWNLOVERS WALK RONDEBOSCH CAPE TOWN 7701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Barth, Stefan Munich, DE 35 98
Hussain, Ahmad Aachen, DE 3 4
Tur, Mehmet K Aachen, DE 1 4

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