Process for preparing stable pharmaceutical compositions of compounds susceptible to hydrolysis

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United States of America Patent

PATENT NO 9872873
SERIAL NO

14377047

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Abstract

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The present invention relates to a process of preparing a stable pharmaceutical composition of compounds which are susceptible to hydrolysis comprising a. Addition of required quantity of pharmaceutically acceptable lyophilization excipients optionally in Water for Injection in a formulation vessel; b. Addition of organic solvent to form a appropriate proportion of aqueous and organic solvent; c. Maintaining the temperature of the formulation vessel from the range −5±1° C. to −5±3° C.; d. Addition of required quantity of compound susceptible to hydrolysis to form a solution and lyophilizing the solution.

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Patent Owner(s)

Patent OwnerAddress
FRESENIUS KABI ONCOLOGY LIMITEDNEW DELHI 110 066

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bhandari, Vikas Gurgaon, IN 3 8
Chandel, Vikas Gurgaon, IN 4 30
Garg, Minakshi Gurgaon, IN 3 22
Khanna, Rajesh Gurgaon, IN 48 4058
Khattar, Dhiraj Gurgaon, IN 26 202
Kumar, Kyama Vijay Gurgaon, IN 1 6
Motwani, Sanjay Gurgaon, IN 2 6
Yadav, Mukti Gurgaon, IN 4 19

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