Methods of treatment using selective Bcl-2 inhibitors
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United States of America Patent
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Jan 23, 2018
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app pub date -
Apr 22, 2016
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Nov 23, 2010
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Abstract
This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-XL.
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