Time reversal optical tomography for locating targets in a highly scattering turbid medium

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United States of America Patent

PATENT NO 9867542
SERIAL NO

14060221

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A time reversal optical tomography (TROT) method for near-infrared (NM) diffuse optical imaging of targets embedded in a highly scattering turbid medium is presented. TROT combines the basic symmetry of time reversal invariance and subspace-based signal processing for retrieval of target location. The efficacy of TROT is tested using simulated data and data obtained from NIR imaging experiments on absorptive, scattering and fluorescent targets embedded in Intralipid-20% suspension in water, as turbid medium, as well as, a realistic cancerous model breast assembled using ex vivo human breast tissues with two embedded tumors. The results demonstrate the potential of TROT for detecting and locating small targets in a turbid medium, such as, breast tumors in early stages of growth.

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RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK230 WEST 41ST STREET 7TH FLOOR NEW YORK NY 10036

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Inventor Name Address # of filed Patents Total Citations
Cai, Wei Bronx, US 73 1216
Gayen, Swapan K Marlboro, US 4 167
Wu, Binlin Forest Hills, US 2 23

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