Method for determining the repair activity of non-homologous end joining

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United States of America Patent

PATENT NO 9863933
SERIAL NO

15310491

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Abstract

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The invention discloses a method for determining the repair activity of NHEJ. In this method, HPRT gene is mutated by using a site-directed gene mutation technology, and plasmid transfection, and 6-TG treatment are performed. By means of the method of the invention, the NHEJ repair activity level of cells can be observed by measuring the cell viability. The method can be used for screening the effects of different drugs and different genes on the NHEJ repair activity.

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Patent OwnerAddress
SOOCHOW UNIVERSITY215000 TEN 1 ZI STREET JIANGSU SUZHOU SUZHOU CITY JIANGSU PROVINCE 215000

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Du, Jie Jiangsu, CN 79 446
Liu, Fenju Jiangsu, CN 2 0
Shang, Zengfu Jiangsu, CN 1 0
Yu, Jiahua Jiangsu, CN 4 17
Zhang, Haowen Jiangsu, CN 11 3
Zhang, Yushuo Jiangsu, CN 3 0

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