Dual-pore device
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United States of America Patent
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Jan 9, 2018
Grant Date -
Jun 11, 2015
app pub date -
Nov 29, 2014
filing date -
Jul 20, 2011
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Abstract
Provided is a device comprising an upper chamber, a middle chamber and a lower chamber, wherein the upper chamber is in communication with the middle chamber through a first pore, and the middle chamber is in communication with the lower chamber through a second pore, wherein the first pore and second pore are about 1 nm to about 100 nm in diameter, and are about 10 nm to about 1000 nm apart from each other, and wherein each of the chambers comprises an electrode for connecting to a power supply. Methods of using the device are also provided, in particular for sequencing a polynucleotide.
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