Long noncoding RNAs and cell reprogramming and differentiation

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United States of America Patent

PATENT NO 9862943
SERIAL NO

14703618

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Abstract

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Long noncoding RNAs (lncRNAs) are identified that enhance pluripotency reprogramming of somatic cells as well as differentiation of pluripotent cells. Induced pluripotent stem (iPS) cell generation from somatic cells leads to the upregulation and downregulation of identified lncRNAs. The modulation of these lncRNAs are capable of enhancing pluripotency of somatic cells as well as enhancing differentiation of a pluripotent cell.

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Patent Owner(s)

Patent OwnerAddress
CALIFORNIA INSTITUTE OF TECHNOLOGY1200 E CALIFORNIA BLVD M/C 6-32 PASADENA CA 91125

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Daniel H Los Angeles, US 153 14147
Wold, Barbara J San Marino, US 13 276

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