Method for determining cell state and autoanalyzer using said method

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United States of America Patent

PATENT NO 9862921
SERIAL NO

14896123

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Abstract

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There is provided a method for noninvasively evaluating the cell state (proliferation, multi-layering, and differentiation) of a cell sheet as a mimic tissue at the time of culturing the cell sheet. The method is characterized in that an analysis of an amino acid is conducted with the use of the culture supernatant of a cell sheet to monitor a change in the concentration of any amino acid selected from a group of 5-species of amino acids (Ile, Val, Ser, Leu, and Ala), thereby making a determination.

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Patent Owner(s)

Patent OwnerAddress
HITACHI HIGH-TECH CORPORATION17-1 TORANOMON 1-CHOME MINATO-KU TOKYO 105-6409

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Imai, Kazumichi Tokyo, JP 45 766
Inoue, Yoko Tokyo, JP 33 137
Nakagawa, Hiroaki Tokyo, JP 96 388
Nakajima, Ryota Tokyo, JP 33 135
Senda, Naoko Tokyo, JP 11 49
Shimase, Akihiro Tokyo, JP 13 74
Takeda, Shizu Tokyo, JP 11 13

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