Pharmaceutical composition for treatment and/or prevention of cancer

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United States of America Patent

PATENT NO 9862774
SERIAL NO

14910878

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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It is intended to provide a CAPRIN-1-targeting antibody superior in antitumor activity to conventional antibodies, and use thereof as a therapeutic and/or preventive agent for a cancer. The present invention provides an antibody targeting a CAPRIN-1 polypeptide specifically expressed on the surface of cancer cells, and use of the antibody as a therapeutic and/or preventive agent for a cancer. The present invention provides an antibody which comprises a heavy chain variable region comprising complementarity-determining regions of SEQ ID NOs: 1, 2, and 3 and a light chain variable region comprising complementarity-determining regions of SEQ ID NOs: 4, 5, and 6 and has immunological reactivity with a CAPRIN-1 protein, or a fragment thereof, and a pharmaceutical composition for the treatment and/or prevention of a cancer, comprising this antibody or fragment as an active ingredient.

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Patent Owner(s)

Patent OwnerAddress
TORAY INDUSTRIES INCJAPAN'S TOKYO CENTRAL NIHONBASHI MUROMACHI 2 CHOME 1 NO 1 TOKYO TOKYO METROPOLIS

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ido, Takayoshi Kanagawa, JP 15 201
Minamida, Yoshitaka Kanagawa, JP 18 217
Okano, Fumiyoshi Kanagawa, JP 74 724
Saito, Takanori Kanagawa, JP 113 2068

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