Methods and apparatus for stimulating and recording neural activity

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United States of America Patent

PATENT NO 9861810
SERIAL NO

13919594

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Abstract

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Thermal drawing processes can be used to make multifunctional, high-resolution neural probes for neural recording and stimulation. An exemplary neural probe may include one or more conductive fibers or microelectrodes coated with two or more layers of insulating material, at least one of which is partially etched to expose a tip at the neural probe's distal end. The conductive fibers conduct electrical signals (e.g., neural spikes or electrical stimulation) between the tip and the neural probe's proximal end. Optional optical and fluidic waveguides may guide light and fluid, respectively, between the tip and the proximal end. A neural probe may be flexible enough for long-term (chronic) implantation in neural tissue (e.g., the brain) without excessive tissue damage, even during movement of the brain in the skull. The probe may be made from biocompatible materials, such as insulating and conductive polymers, that have negligible (insignificant) interaction with the surrounding tissue.

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Patent OwnerAddress
MASSACHUSETTS INSTITUTE OF TECHNOLOGY77 MASSACHUSETTS AVENUE CAMBRIDGE MA 02139

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Anikeeva, Polina Olegovna Somerville, US 12 68
Canales, Andres Brighton, US 4 24
Fink, Yoel Brookline, US 85 3365
Froriep, Ulrich Paul Brighton, US 1 24
Jia, Xiaoting Somerville, US 8 44
Lu, Chi Cambridge, US 12 411
Tringides, Christina Myra Cambridge, US 2 27

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