PSMA-binding agents and uses thereof

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United States of America Patent

PATENT NO 9861713
SERIAL NO

14987032

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Abstract

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Prostate-specific membrane antigen (PSMA) binding compounds having radioisotope substituents are described, as well as chemical precursors thereof. Compounds include pyridine containing compounds, compounds having phenylhydrazine structures, and acylated lysine compounds. The compounds allow ready incorporation of radionuclides for single photon emission computed tomography (SPECT) and positron emission tomography (PET) for imaging, for example, prostate cancer cells and angiogenesis.

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Patent Owner(s)

  • THE JOHNS HOPKINS UNIVERSITY

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Ying Lutherville-Timonium, US 944 21963
Mease, Ronnie Charles Fairfax, US 7 295
Pomper, Martin G Baltimore, US 90 527

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